Kalydeco: The most important new drug of 2012
Kalydeco, a drug for cystic fibrosis, is the most important new drug of 2012 according to Forbes magazine and was developed by Vertex pharmaceuticals with seed funding from the Cystic Fibrosis Foundation.
Cystic Fibrosis is a genetic disorder that results in scarring (fibrosis) and cyst formation within the pancreas, lungs, liver, and intestines.
Kalydeco, given alone, will only help a few thousand patients the world over. Like other drugs for very rare diseases, its price is very high: $294,000 per patient per year.
Though its chemical structure could be routinely made by a synthetic chemist, it is covered by a patent so it is illegal to make in a lab.
The efforts to cure cystic fibrosis were spearheaded by a discovery from Francis Collins, later famous for heading the Human Genome Project and then the National Institutes of Health, who discovered the gene that, when mutated, causes cystic fibrosis 23 years ago. Kalydeco is the first drug to directly affect the defects caused by these mutations, leading to improvements in patients’ lung function.
Posted on January 8, 2013, in chemistry in everyday life, drugs. Bookmark the permalink. 8 Comments.
Using ingenious technology and innovation the Romans made an Empire that withstood the test of your time.
The simple truth is, people join MLM opportunities
because of who introduced them. The business degree raises one’s social standing: in other words, it
opens to suit your needs doors that will have otherwise remained closed
for your requirements.
Bulks in the advertisers are primarily private house owners, letting managers and property agents.
An HVAC repair clients are most often started by the technician who’s
learned the trade through previous employment. it also can be
employed for headhunting and employment.
Using ingenious technology and innovation the Romans made an Empire that
withstood the test of your time. So unless any organization completes the
formalities and find the necessary certifications they’re able to’t start their business.
” The company sees innovation as certainly one of its core organizational competencies.
The dedicated team of AVG professionals is accessible
here all round the time, whom it is possible to reach by calling around the AVG
tech support number. The truth is, people join MLM opportunities as
a consequence of who introduced them. If you’re still in a loss, it is
possible to contact the consumer care team
either by email, live chat, or phone during standard west coast business hours.
Often we hear experts on television that
report a certain stock is gonna soar and now will be the time to buy.
She invites that you visit her site where she’s going to share a proven approach to start an business online.
” The company sees innovation as among its core organizational competencies.
My partner and I stumbled over here from a different
page and thought I should check things out. I like what I see so i am just
following you. Look forward to exploring your web
Great looking internet site. Presume you did a great deal of your very own html coding.
One major advantage of a non-recourse agreement is that once you have sold the accounts
receivable, it is no longer your responsibility. Lastly, reputable invoice factoring companies, such as those affiliated with Factors Against Fraud
and the International Factoring Association, will provide online account access and 24-hour client
support either online or by phone. The primary difference between recourse factoring
and non-recourse factoring is the party who is at risk if your customer does not
pay the invoice.