# How are drugs designed?

How are drugs designed? Come on Friday 2nd May at 18:00 at the Athens Science Festival, Technopolis Gkazi to listen to my talk! See the detailed program of the festival here.

This talk will address how drugs are designed to combat a disease – from the discovery of the cause of the disease (e.g. a mutant protein), specialized techniques for the design of small chemical molecules (that are drugs), to clinical trials. We will also discuss advances and progresses in individualized treatment (also known as personalized medicine), i.e. how DNA testing could help each patient receive medication specifically tailored for them.

Πώς σχεδιάζονται τα φάρμακα; Ελάτε την Παρασκευή 2 Μαϊου στις 18:00 στο Athens Science Festival, Τεχνοπολις Γκάζι, να ακούσετε την ομιλία μου.

Η ομιλία έχει θέμα το πώς επιτελείται ο σχεδιασμός φαρμάκων για μία ασθένεια – από την ανακάλυψη του αιτίου που προκαλεί την ασθένεια (π.χ. μια μεταλλαγμένη πρωτεΐνη), εξειδικευμένες τεχνικές για το σχεδιασμό μικρών χημικών μορίων που αποτελούν τα φάρμακα, μεχρι και τις κλινικές δοκιμές. Επίσης θα συζητήσουμε τις προοπτικές και εξελίξεις στην εξατομικευμένη θεραπεία, το πώς δηλαδή με εξέταση DNA μπορεί ο κάθε ασθενής να λαμβάνει ένα φάρμακο που είναι ειδικά κατάλληλο για εκείνον.

Περισσότερες πληροφορίες και μία μικρή περίληψη για το θέμα θα βρείτε σε πρόσφατο άρθρο στην ιστοσελίδα της διοργάνωσης.

Posted on April 30, 2014, in chemistry and everyday life, chemistry in everyday life, computational chemistry, drugs and tagged drug design. Bookmark the permalink. 4 Comments.

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Definition 16 (Locally uniform convergence) A sequence of functions converges locally uniformly to a limit if, for every bounded subset of , converges uniformly to on . In other words, for every bounded and every , there exists such that for all and .

Remark 6 At least as far as is concerned, an equivalent definition of local uniform convergence is: converges locally uniformly to if, for every point , there exists an open neighbourhood of such that converges uniformly to on . The equivalence of the two definitions is immediate from the Heine-Borel theorem. More generally, the adverb “locally” in mathematics is usually used in this fashion; a propery is said to hold locally on some domain

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